Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC424H656N120O114S6

DescriptionStandard

        TPLVQSYPNTVQTVLFLLVSQDSGTGLAHRSLDRQGTWEKCWNLLGKCRHTCFKKERIYVYCTNSKPCCVKPKYHPKQHPW
    

Molecular Weight9450.87 Da

Isoelectric Point (pI)9.44

Net Charge (pH 7.0)7.68

Net Charge (pH 7.4) 7.18

Charge Density (pH 7.0) 0.0949

GRAVY Index-0.61

Hydrophobic Moment 0.55

Boman Index-0.09

Instability Index27.26

Aliphatic Index 66.05

Aromaticity 0.1111

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3774.03

LogP -35.65

H-bond Donors 137.0

H-bond Acceptors 132.0

Rotatable Bonds 302.0

Heavy Atoms 664.0

Ring Count 22.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0261468 VERIFIED: NO

Provenance & Taxonomy

OrganismMyotis lucifugus [Animal]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0398452 VERIFIED: NO

Provenance & Taxonomy

OrganismMyotis lucifugus [Animal]

FamilyDefensin

Tax ID59463

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence