Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC359H572N98O91S10

DescriptionStandard

        MTQLLLLIMTLLVLGHLPPGKCEFKRCWRGQGACRTYCTRQEAFMHLCPDASLCCLPYGIKPQPPPKPEHV
    

Molecular Weight8037.63 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)3.70

Net Charge (pH 7.4) 3.21

Charge Density (pH 7.0) 0.0521

GRAVY Index-0.02

Hydrophobic Moment 0.60

Boman Index0.08

Instability Index53.51

Aliphatic Index 83.80

Aromaticity 0.0704

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2937.89

LogP -20.99

H-bond Donors 105.0

H-bond Acceptors 108.0

Rotatable Bonds 252.0

Heavy Atoms 558.0

Ring Count 18.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326490 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic