Peptide Database

Peptide NameproADM 45–92 (Adrenomedullin)

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC215H359N67O73S2

DescriptionStandard

        ELRMSSSYPTGLADVKAGPAQTLIRPQDMKGASRSPEDSSPDAARIRV
    

Molecular Weight5114.69 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.66

Charge Density (pH 7.0) 0.0175

GRAVY Index-0.68

Hydrophobic Moment 0.51

Boman Index-0.17

Instability Index87.49

Aliphatic Index 65.21

Aromaticity 0.0208

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2260.89

LogP -29.83

H-bond Donors 79.0

H-bond Acceptors 76.0

Rotatable Bonds 167.0

Heavy Atoms 357.0

Ring Count 6.0

Amide Bonds 49.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0064109 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Vasodilator

MethodSandwich immunoluminometric Assay

Half-LifeHuman blood plasma, in vitro; 1320 s