‹ ›
MYP_056811
← PREVIOUS NEXT → BACK
Basic Information
HCV gp (696-710), E2-79
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
15 amino acids
C80H122N20O24S
Standard
Sequence
LHQNIVDVQYMYGLS
Physicochemical Analysis
1780.01 Da
5.08
-1.15
-1.41
-0.0769
0.09
0.28
0.22
57.34
116.67
0.1333
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
726.66
-5.24
24.0
25.0
57.0
125.0
3.0
17.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0103982 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
5/CD81 cells
0.001 μM
IC50
PMID28638089 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28638089/
RECORD: Rec_0116278 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Human hepatocellular carcinoma Huh7.5/CD81
>0.1 μM
Cytotoxicity
PMID28638089 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28638089/
RECORD: Rec_0133870 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HCV(Hepatitis C virus):inhibition of HCVcc infection in Huh7
PMID28638089 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28638089/
RECORD: Rec_0211177 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Hepatitis C virus (HCV)
PMID28638089 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28638089/
RECORD: Rec_0225675 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCV Entry inhibition
HCV (Hepatitis C virus) | Huh7.5/CD81 cells
0.001-0.005 μM
IC50
Mammalian: 5.5 h; Yeast: 3 min; E. coli: 2 min
PaperA screen for inhibitory peptides of hepatitis C virus identifies a novel entry inhibitor targeting E1 and E2. | Yin P, Zhang L, Ye F, Deng Y, Lu S, Li YP, Zhang L, Tan W. | A screen for inhibitory peptides of hepatitis C virus identifies a novel entry inhibitor targeting E1 and E2. | DOI:10.1038/s41598-017-04274-8 | PMID:28638089 PMID28638089 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28638089/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2