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MYP_056799
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Basic Information
Magainin-M1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
23 amino acids
C113H179N29O28S
Standard
Sequence
GIGKFLHSAGKFGKAFIGEIMKS
Physicochemical Analysis
2423.87 Da
10.00
2.85
2.59
0.1237
0.23
0.64
0.24
-0.10
76.52
0.1304
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
914.04
-6.74
32.0
33.0
85.0
171.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0083351 VERIFIED: YES
Provenance & Taxonomy
Xenopus muelleri [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
25 μM
MIC
PaperPeptidomic analysis of skin secretions demonstrates that the allopatric populations of Xenopus muelleri (Pipidae) are not conspecific
RECORD: Rec_0138580 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
180 μM
LC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/21664395/ PMID21664395 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21664395/
RECORD: Rec_0145193 VERIFIED: YES
Provenance & Taxonomy
Xenopus muelleri [Animal]
Magainin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperM. Mechkarska et al. / Peptides 32 (2011) 1502-1508. Peptidomic analysis of skin secretions demonstrates that the allopatric populations of Xenopus muelleri (Pipidae) are not conspecific
RECORD: Rec_0181174 VERIFIED: YES
Provenance & Taxonomy
Xenopus muelleri [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic Anti-Gram-positive
Staphylococcus aureus
50 μM
MIC
RECORD: Rec_0183323 VERIFIED: YES
Provenance & Taxonomy
Xenopus muelleri [Animal]
Magainin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic
Hemolytic activity
180 μM
LC50
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