Peptide Database

Peptide NameConotoxin Cal6.5a

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC125H187N33O41S6

DescriptionStandard

        DDCTTYCYGVHCCPPAFKCAASPSCKQT
    

Molecular Weight3000.41 Da

Isoelectric Point (pI)6.69

Net Charge (pH 7.0)-0.21

Net Charge (pH 7.4) -0.56

Charge Density (pH 7.0) -0.0076

GRAVY Index-0.20

Hydrophobic Moment 0.36

Boman Index0.02

Instability Index76.18

Aliphatic Index 21.07

Aromaticity 0.1071

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1162.67

LogP -15.36

H-bond Donors 45.0

H-bond Acceptors 48.0

Rotatable Bonds 87.0

Heavy Atoms 205.0

Ring Count 7.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0115425 VERIFIED: NO

Provenance & Taxonomy

OrganismConus californicus [Animal]

FamilyConotoxin

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-13, 7-19, 12-25

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0162330 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 10.7%, E 0.0%, T 39.3%, C 50.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic