Peptide Database

Peptide NamedacC signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC153H251N35O35S2

DescriptionStandard

        MKKSIKLYVAVLLLFVVASVPYMHQAALA
    

Molecular Weight3204.97 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)2.58

Net Charge (pH 7.4) 2.31

Charge Density (pH 7.0) 0.0891

GRAVY Index1.24

Hydrophobic Moment 0.41

Boman Index0.42

Instability Index45.34

Aliphatic Index 147.93

Aromaticity 0.1034

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1100.08

LogP -2.62

H-bond Donors 38.0

H-bond Acceptors 41.0

Rotatable Bonds 104.0

Heavy Atoms 225.0

Ring Count 5.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0193002 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Natto phytase secretion

TargetBacillus subtilis RIK1285

Activity4.263 U/mL

MethodPhytase activity assay

RECORD: Rec_0195544 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

Activity1.46 U/mL

MethodCutinase activity assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/