Peptide Database

Peptide NameP4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC119H190N32O22

DescriptionStandard

        YFRTIRRFFKKLFKTLKK
    

Molecular Weight2420.98 Da

Isoelectric Point (pI)11.76

Net Charge (pH 7.0)7.75

Net Charge (pH 7.4) 7.54

Charge Density (pH 7.0) 0.4308

GRAVY Index-0.69

Hydrophobic Moment 1.06

Boman Index-0.37

Instability Index15.13

Aliphatic Index 65.00

Aromaticity 0.2778

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 934.51

LogP -3.11

H-bond Donors 36.0

H-bond Acceptors 30.0

Rotatable Bonds 85.0

Heavy Atoms 173.0

Ring Count 5.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0234410 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive

TargetStaphylococcus aureus ATCC 25923

Activity64 μg/mL

MethodMIC

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