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MYP_056732
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Basic Information
P4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
18 amino acids
C119H190N32O22
Standard
Sequence
YFRTIRRFFKKLFKTLKK
Physicochemical Analysis
2420.98 Da
11.76
7.75
7.54
0.4308
-0.69
1.06
-0.37
15.13
65.00
0.2778
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
934.51
-3.11
36.0
30.0
85.0
173.0
5.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0039583 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
S. sangui ATCC 10556
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0084009 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Murine blood [HC10 = 640 microg/mL, HC50 = >640 microg/mL, Percent Hemolysis ± SD Hmax (100%) = 10.30 ± 2.5]
640 μg/mL
HC50
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0118971 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
S. mutans ATCC UA159
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0162024 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
MRSA 18466
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
RECORD: Rec_0172093 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Candida albicans ATCC 5314
64 μg/mL
MIC
PMID31520928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31520928/
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