Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC677H1117N199O198S14

DescriptionStandard

        MKSLLFTLSSFMLLTQLVSGNWYVRKCANKTGNCRSVCRPGEMATVPPTGMCPKEKMCCILSACGETTKTTNSAQASESSTTTPGPRTSPRVSPELRSLLHKAKGFTLVSLFLLHPLALPLHATMSGRASHLFSTSRARGGMQIR
    

Molecular Weight15661.24 Da

Isoelectric Point (pI)10.16

Net Charge (pH 7.0)12.78

Net Charge (pH 7.4) 12.24

Charge Density (pH 7.0) 0.0882

GRAVY Index-0.09

Hydrophobic Moment 0.66

Boman Index0.01

Instability Index43.69

Aliphatic Index 72.69

Aromaticity 0.0483

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6319.67

LogP -76.59

H-bond Donors 233.0

H-bond Acceptors 229.0

Rotatable Bonds 513.0

Heavy Atoms 1088.0

Ring Count 22.0

Amide Bonds 151.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0044783 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris (Dog) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0250703 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence