Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC317H518N76O89S

DescriptionStandard

        MELIIADLTAYTGISTAWATVIVNAINVGSTVIALASIFASAGLSAGLILVVKEFVKKNGTKAAIAW
    

Molecular Weight6850.02 Da

Isoelectric Point (pI)8.14

Net Charge (pH 7.0)0.50

Net Charge (pH 7.4) 0.28

Charge Density (pH 7.0) 0.0075

GRAVY Index1.10

Hydrophobic Moment 0.53

Boman Index0.44

Instability Index-1.49

Aliphatic Index 137.01

Aromaticity 0.0746

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2603.51

LogP -20.68

H-bond Donors 92.0

H-bond Acceptors 91.0

Rotatable Bonds 224.0

Heavy Atoms 483.0

Ring Count 7.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126558 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus woosongensis [Bacterium]

FamilyBacteriocin

Tax ID307580

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal