Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC546H884N148O165S2

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPVSGIKLVIGNASLTIDMNWNIRTWIFKDSGRGTVHISKVFVTAIFSTPLDNTGPTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12225.88 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)3.21

Net Charge (pH 7.4) 2.97

Charge Density (pH 7.0) 0.0282

GRAVY Index0.09

Hydrophobic Moment 0.54

Boman Index0.13

Instability Index18.94

Aliphatic Index 102.54

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4996.07

LogP -55.60

H-bond Donors 178.0

H-bond Acceptors 173.0

Rotatable Bonds 403.0

Heavy Atoms 861.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0227996 VERIFIED: NO

Provenance & Taxonomy

OrganismPtilorrhoa leucosticta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria