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MYP_056624
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Basic Information
[I5,R8] Mastoparan-L ([I5,R8]
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C76H143N21O16
Standard
Sequence
INLKILARLAKKIL
Physicochemical Analysis
1607.08 Da
11.26
3.76
3.55
0.2684
0.90
0.84
0.13
18.61
209.29
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
624.67
-1.41
22.0
20.0
59.0
113.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0209929 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
12.5 μM
MIC
PMID27423268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27423268/
RECORD: Rec_0214172 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Klebsiella pneumoniae ATCC 13883
6.25 μM
MIC
PaperSelective amino acid substitution reduces cytotoxicity of the antimicrobial peptide mastoparan.
RECORD: Rec_0263107 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Streptococcus pyogenes ATCC 19615
6.25 μM
MIC
PMID27423268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27423268/
RECORD: Rec_0280491 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans ATCC 90028
12.5 μM
MIC
PMID27423268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27423268/
RECORD: Rec_0303399 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Listeria ivanovii Li 4pVS2
50 μM
MIC
PMID27423268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27423268/
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