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MYP_056624
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Basic Information
[I5,R8] Mastoparan-L ([I5,R8]
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C76H143N21O16
Standard
Sequence
INLKILARLAKKIL
Physicochemical Analysis
1607.08 Da
11.26
3.76
3.55
0.2684
0.90
0.84
0.13
18.61
209.29
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
624.67
-1.41
22.0
20.0
59.0
113.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0143238 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
HEK-293 cells
>200 μM
IC50
PaperSelective amino acid substitution reduces cytotoxicity of the antimicrobial peptide mastoparan. PMID27423268
RECORD: Rec_0149211 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Candida parapsilosis ATCC 22019
25 μM
MIC
PaperSelective amino acid substitution reduces cytotoxicity of the antimicrobial peptide mastoparan. PMID27423268
RECORD: Rec_0159595 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
6.25 μM
MIC
PMID27423268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27423268/
RECORD: Rec_0170072 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Candida albicans ATCC 90028
12.5 μM
MIC
PaperSelective amino acid substitution reduces cytotoxicity of the antimicrobial peptide mastoparan. PMID27423268
RECORD: Rec_0196285 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 90028
12.5 μM
MIC
PMID27423268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27423268/
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