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MYP_056618
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Basic Information
Esculentin-1ISb (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
46 amino acids
C216H380N62O59S3
Standard
Sequence
RIFSKIGGKAIKNLILKGIKNIGKEVGMDVIRTGIDVAGCKIKGEC
Physicochemical Analysis
4885.90 Da
9.83
5.74
5.49
0.1248
0.18
0.78
0.07
8.28
116.52
0.0217
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1980.62
-17.00
71.0
68.0
179.0
340.0
1.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0265541 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
40-46
Bio-Activity Profile
Antimicrobial Antifungal
Bacillus subtilis
12.5 μM
MIC
PaperIdentification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae
RECORD: Rec_0270001 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Esculentin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
40-46
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus MRSA
3.1-12.5 μM
MIC
PaperIdentification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae
RECORD: Rec_0282875 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Esculentin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
40-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
3.1 μM
MIC
PaperE. Iwakoshi-Ukena et al. / Peptides 32 (2011) 670-676. Identification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae PMID21193000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21193000/
RECORD: Rec_0299751 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Esculentin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
40-46
Bio-Activity Profile
Antimicrobial Antifungal
PaperE. Iwakoshi-Ukena et al. / Peptides 32 (2011) 670-676. Identification and characterization of antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae PMID21193000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21193000/
RECORD: Rec_0322085 VERIFIED: YES
Provenance & Taxonomy
Odorrana ishikawae [Animal]
Esculentin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
40-46
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
3.1 μM
MIC
PMID21193000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21193000/
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