Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length498 amino acids

Chemical FormulaC2469H3884N668O687S14

DescriptionStandard

        MGAGGGRTGRERRAAAGMAARSLAAFGAVLAVCLALTAATNPGFVVRITQAGLDYAHQHGITVLQKELAKLKLPDISGDFPVRRLGKVRYEISSLDLRSFHLPYSRISLVPNVGLQVAISNAFAEVDGNWRVKFHFIRDHGSFNLEVKNVYIKIDLKLGNDASGKPTVSTSACSTRISSVDVHFSGKFGWLYNLFYSAVESRFKKILESKVCDSVVRSVGGDLQHYLQTLPVTAKIDARAGIDYSLVAPPMATAQTLDVDLKGEFFSLAHRGAVPFPPPVLALPPDHDRMVYFGASSYFFNTAGFAYHAAGALVYEITDSMIPKGVEFHLNTSTFAAFIPQLDEMYPNMLMKLRLSAPSAPFLSITPGGISLQPVVDIQAYAILPNTSLAHLFLLSLTGNVSATIDVKSGHIVGKLTVGRMKLSLKHSDVGTFQVRMLQSIMNIYASSILLPRVNERLAEGFPLPLPDRIQLSNILVQFHQNFLLLGADVHYTPREHR
    

Molecular Weight54366.22 Da

Isoelectric Point (pI)9.36

Net Charge (pH 7.0)10.98

Net Charge (pH 7.4) 9.77

Charge Density (pH 7.0) 0.0221

GRAVY Index0.15

Hydrophobic Moment 0.70

Boman Index0.14

Instability Index33.64

Aliphatic Index 100.08

Aromaticity 0.0924

Extinction Coeff. Reduced 34840.00

Extinction Coeff. Oxidized 34965.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419967 VERIFIED: NO

Provenance & Taxonomy

OrganismMeleagris gallopavo [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria