Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC262H403N77O77S8

DescriptionStandard

        GRTEFKRCWKGQGTCRTYCTRQESFIHLCPDASLCCLSYMFRPSRPPMPEDE
    

Molecular Weight6119.99 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.80

Net Charge (pH 7.4) 1.44

Charge Density (pH 7.0) 0.0347

GRAVY Index-0.77

Hydrophobic Moment 0.54

Boman Index-0.21

Instability Index84.91

Aliphatic Index 31.92

Aromaticity 0.1154

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2483.66

LogP -26.58

H-bond Donors 94.0

H-bond Acceptors 88.0

Rotatable Bonds 194.0

Heavy Atoms 424.0

Ring Count 13.0

Amide Bonds 53.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0051290 VERIFIED: NO

Provenance & Taxonomy

OrganismHeterocephalus glaber [Animal]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0125449 VERIFIED: NO