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MYP_056527
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Basic Information
STPk
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
11 amino acids
C87H122N20O12
Standard
Sequence
KKFKWWWKFKK
Physicochemical Analysis
1640.03 Da
10.70
5.75
5.54
0.5231
-1.86
0.41
-0.38
-18.24
0.00
0.4545
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
557.81
2.68
21.0
18.0
55.0
119.0
8.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0150024 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Nlys [NH2 –(CH2)4 –NH–CH2 –COOH].
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli KCTC 1682
1 μM
MIC
PMID17604338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17604338/
RECORD: Rec_0158163 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is lysine peptoid residue [NH2-(CH2)4-NH-CH2-COOH]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID17604338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17604338/
RECORD: Rec_0188879 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Nlys [NH2 –(CH2)4 –NH–CH2 –COOH].
Bio-Activity Profile
Hemolytic
Human erythrocytes
200 μM
MHC
PMID17604338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17604338/
RECORD: Rec_0213528 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is lysine peptoid residue [NH2-(CH2)4-NH-CH2-COOH]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis(KCTC 1917)
1 μM
MIC
PMID17604338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17604338/
RECORD: Rec_0232991 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is lysine peptoid residue [NH2-(CH2)4-NH-CH2-COOH]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MRSA2 (CCARM 3543)
0.5 μM
MIC
PMID17604338 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17604338/
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