Peptide Database

Peptide NameCholesterol 25-hydroxylase

Function Ontology

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length272 amino acids

Chemical FormulaC1498H2180N376O363S15

DescriptionStandard

        MSCHNCSDPQVLCSSGQLFLQPLWDHLRSWEALLQSPFFPVIFSITTYVGFCLPFVVLDILCSWVPALRRYKIHPDFSPSAQQLLPCLGQTLYQHVMFVFPVTLLHWARSPALLPHEAPELLLLLHHILFCLLLFDMEFFVWHLLHHKVPWLYRTFHKVHHQNSSSFALATQYMSVWELFSLGFFDMMNVTLLGCHPLTTLTFHVVNIWLSVEDHSGYNFPWSTHRLVPFGWYGGVVHHDLHHSHFNCNFAPYFTHWDKILGTLRTASVPAR
    

Molecular Weight31744.61 Da

Isoelectric Point (pI)6.77

Net Charge (pH 7.0)-1.48

Net Charge (pH 7.4) -3.08

Charge Density (pH 7.0) -0.0054

GRAVY Index0.30

Hydrophobic Moment 0.66

Boman Index0.26

Instability Index61.81

Aliphatic Index 98.12

Aromaticity 0.1581

Extinction Coeff. Reduced 72420.00

Extinction Coeff. Oxidized 72920.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085483 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyCH25H

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsN-glycosylation Asn5, Asn163, Asn189

Bio-Activity Profile

Function

Antiviral Entry inhibitor Replication inhibitor

TargetSARS-CoV-2

Activity1.49 μM

MethodEC50