Peptide Database

Peptide NameBeta-defensin 7 (BNBD-7) (BNDB-7)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC306H508N100O72S7

DescriptionStandard

        MRLHHLLLALLFLVLSAGSGFTQGVRNFVTCRINRGFCVPIRCPGHRRQIGTCLGPRIKCCR
    

Molecular Weight6964.39 Da

Isoelectric Point (pI)11.47

Net Charge (pH 7.0)9.70

Net Charge (pH 7.4) 9.24

Charge Density (pH 7.0) 0.1565

GRAVY Index0.35

Hydrophobic Moment 0.76

Boman Index0.04

Instability Index20.73

Aliphatic Index 103.71

Aromaticity 0.0645

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2754.72

LogP -25.72

H-bond Donors 106.0

H-bond Acceptors 92.0

Rotatable Bonds 228.0

Heavy Atoms 485.0

Ring Count 10.0

Amide Bonds 65.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0160320 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0327794 VERIFIED: YES