Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC273H432N68O84S6

DescriptionStandard

        METEKYLQVVEDEEIEQLVGGAGPGWVETLTKDCPWNMPVACVTILGQRICKKCY
    

Molecular Weight6203.15 Da

Isoelectric Point (pI)4.48

Net Charge (pH 7.0)-4.52

Net Charge (pH 7.4) -4.82

Charge Density (pH 7.0) -0.0822

GRAVY Index-0.15

Hydrophobic Moment 0.50

Boman Index0.08

Instability Index67.44

Aliphatic Index 84.91

Aromaticity 0.0727

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2435.35

LogP -18.90

H-bond Donors 85.0

H-bond Acceptors 86.0

Rotatable Bonds 204.0

Heavy Atoms 431.0

Ring Count 9.0

Amide Bonds 58.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0285750 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus cereus [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria