Peptide Database

Peptide NamePEG-Magainin-2 [E19Q]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC114H181N31O28S

DescriptionStandard

        GIGKFLHSAKKFGKAFVGQIMNS
    

Molecular Weight2465.91 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.84

Net Charge (pH 7.4) 3.58

Charge Density (pH 7.0) 0.1671

GRAVY Index0.08

Hydrophobic Moment 0.69

Boman Index0.17

Instability Index-5.20

Aliphatic Index 72.17

Aromaticity 0.1304

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 962.92

LogP -8.49

H-bond Donors 33.0

H-bond Acceptors 34.0

Rotatable Bonds 86.0

Heavy Atoms 174.0

Ring Count 4.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0349329 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus epidermidis ATCC 12228

Activity80 μM

MethodMIC

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