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MYP_056442
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Basic Information
(1-9)-Ahx-(38-42) Crot
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
15 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
YKQCHKKGGXKKGSG
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0053099 VERIFIED: YES
Provenance & Taxonomy
Crotalus durissus terrificus [Animal]
Crotamine/CyLoP-1
8732
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Fluorophore labeling
None
N-term detail: Labelled with rhodamine B dye; unspecified/non-canonical residue at positions 10
Bio-Activity Profile
Cell-penetrating peptide
HeLa
Fluorescence-based uptake assay
PMID18983137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18983137/
RECORD: Rec_0156144 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
NrTP2
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Rhodamine conjugation
None
Ahx, 6-aminohexanoic acid
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25620660 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25620660/
RECORD: Rec_0215476 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
NrTP2
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Rhodamine conjugation
None
Non-standard residue symbol(s): -, X
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23707662 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23707662/
RECORD: Rec_0228255 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Crotamine
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine conjugation
None
Non-standard residue symbol(s): X
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID18983137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18983137/
RECORD: Rec_0232777 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine B
None
X=Ahx, 6-aminohexanoic acid
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID25620660 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25620660/
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