Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC737H1163N215O216S7

DescriptionStandard

        MAKVQFKPRKETSQIFVHCSATKATMDIGVREIRQWHKEQGWLDIGYHFVIRRDGTIETGRDLGAVGSHVKGYNETSVGVCLVGGIDAKGNHEANFTPQQMASLKNVLTTLKGEWPNAVIMAHHDVAPKACPSFDLSRWLKTGELVTSDRG
    

Molecular Weight16715.88 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)3.10

Net Charge (pH 7.4) 2.45

Charge Density (pH 7.0) 0.0205

GRAVY Index-0.37

Hydrophobic Moment 0.75

Boman Index-0.01

Instability Index29.20

Aliphatic Index 76.16

Aromaticity 0.0728

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6925.33

LogP -71.44

H-bond Donors 244.0

H-bond Acceptors 233.0

Rotatable Bonds 557.0

Heavy Atoms 1175.0

Ring Count 27.0

Amide Bonds 161.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0161867 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterobacter phage phiEap-1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic