Peptide Database

Peptide NameBacteriocin sakacin-P (Sakacin 674)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC280H426N80O86S3

DescriptionStandard

        MEKFIELSLKEVTAITGGKYYGNGVHCGKHSCTVDWGTAIGNIGNNAAANWATGGNAGWNK
    

Molecular Weight6385.06 Da

Isoelectric Point (pI)7.81

Net Charge (pH 7.0)0.66

Net Charge (pH 7.4) 0.30

Charge Density (pH 7.0) 0.0108

GRAVY Index-0.31

Hydrophobic Moment 0.51

Boman Index0.14

Instability Index21.43

Aliphatic Index 64.10

Aromaticity 0.0984

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2677.05

LogP -31.60

H-bond Donors 94.0

H-bond Acceptors 92.0

Rotatable Bonds 209.0

Heavy Atoms 449.0

Ring Count 11.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0426565 VERIFIED: NO

Provenance & Taxonomy

OrganismLactobacillus curvatus [Bacterium]

FamilyBacteriocin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

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