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MYP_056364
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Basic Information
Guanylate-binding protein 7 (EC 3.6.5.-) (GTP-binding protein 7) (GBP-7) (Guanine nucleotide-binding protein 7) (Guanylate-binding protein 4-like)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Enzyme / Catalytic activity ▸ Hydrolase
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
638 amino acids
C3195H5142N894O988S26
Standard
Sequence
MASGPNMEAPVCLVENENEELRVNSKAINILERITQPVVVVAIVGLYRTGKSYLMNRLAGQNHGFNLGTTVRSETKGIWMWCVPHPSKPKFTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLSSTFVYNSMSTINHQALEQLHYVTELTERIRAKSTSRSEEVDDSDEFVSFFPDFIWTVRDFVLELKLEGRVITADEYLENALKLIPGMSIKAQKANLPRECIRHFFPRRKCFVFDRPTKDKELLVHVEEMPEDQLDHSFQVQSKEFCSYIFSNSKAKTLKEGIVVNGNRLATLVTTYVDAINSGDVPCLENAVTTLAQRENSIAVQKAADHYSEQMAQRMRLPTDTLQELLTVHTACEKEAIAVFMEHSFKDENQQFQKNLVVTIEEKKEDFLRQNEAASLSHCQAELDKLSESLRESISRGVFSVPGGHRLYLEARKKVEQDYERVPRKGVKANHVLQSFLQSQISIEDSIMQSDKALTDGQKAMEAERAQKEAAEKEQELLRQKQKELQQVMEAQERSYKENVAQLHEKMETERKNILREQEVKLEHKLKIQKDMLNEGFKRKCEAMDLEISQLQKEIQLNKEKNSSLGAKILDGFGDVLISVVPGSGKYFGLGLKILSSQMNQTQNSDKVRKL
Physicochemical Analysis
72720.09 Da
5.95
-9.13
-10.46
-0.0143
-0.50
0.76
-0.09
40.53
86.16
0.0643
39880.00
40380.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017299 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
T. gondii
PaperThe transcriptional landscape of the mammalian genome; Lineage-specific biology revealed by a finished genome assembly of the mouse; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID15449545;16141072;19468303;15489334;18025219;21183079;21551061;31689351;31964735;33408175 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15449545/
RECORD: Rec_0020535 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Listeria monocytogenes (Gram-positive)
PaperThe transcriptional landscape of the mammalian genome; Lineage-specific biology revealed by a finished genome assembly of the mouse; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID15449545;16141072;19468303;15489334;18025219;21183079;21551061;31689351;31964735;33408175 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15449545/
RECORD: Rec_0048884 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Toxoplasma gondii
PaperThe transcriptional landscape of the mammalian genome; Lineage-specific biology revealed by a finished genome assembly of the mouse; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID15449545;16141072;19468303;15489334;18025219;21183079;21551061;31689351;31964735;33408175 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15449545/
RECORD: Rec_0284757 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
TRAFAC class dynamin-like GTPase; GB1 RHD3 GTPase; GB1 subfamily
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antilisterial Antiparasitic Antiprotozoal Anti-Gram-positive Hydrolase Non-hemolytic
Mycobacterium bovis (Gram-positive)
PaperThe transcriptional landscape of the mammalian genome; Lineage-specific biology revealed by a finished genome assembly of the mouse; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID15449545;16141072;19468303;15489334;18025219;21183079;21551061;31689351;31964735;33408175 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15449545/