Peptide Database

Peptide NameEsculentin-1SN1 antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC414H706N114O119S8

DescriptionStandard

        MFTMKKPMLLIVLLGIISLSLCEQERNADEDEQSEMKRRISFKKGKGSWIKNGIIKGIKGIGKEIGMDVLRTGIDIAGCKIKGEC
    

Molecular Weight9441.25 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)4.48

Net Charge (pH 7.4) 4.19

Charge Density (pH 7.0) 0.0527

GRAVY Index-0.12

Hydrophobic Moment 0.70

Boman Index0.00

Instability Index21.93

Aliphatic Index 100.94

Aromaticity 0.0353

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3798.83

LogP -31.83

H-bond Donors 135.0

H-bond Acceptors 132.0

Rotatable Bonds 344.0

Heavy Atoms 655.0

Ring Count 5.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0072571 VERIFIED: YES

Provenance & Taxonomy

OrganismSylvirana spinulosa [Animal]

Tax ID369515

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0330687 VERIFIED: NO

Provenance & Taxonomy

OrganismHylarana spinulosa [Animal]

FamilyEsculentin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial