Peptide Database

Peptide NameBrevinin-1VLc

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC127H208N28O27S2

DescriptionStandard

        FLPVIASVAAKVLPKVFCFITKKC
    

Molecular Weight2623.31 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.1557

GRAVY Index1.33

Hydrophobic Moment 0.56

Boman Index0.38

Instability Index26.58

Aliphatic Index 125.83

Aromaticity 0.1250

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 859.58

LogP -2.09

H-bond Donors 31.0

H-bond Acceptors 33.0

Rotatable Bonds 83.0

Heavy Atoms 184.0

Ring Count 5.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415190 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates vaillanti [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCandida albicans

Activity3000 μM

MethodMIC

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