Peptide Database

Peptide NameTddefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC178H271N59O48S6

DescriptionStandard

        RYCPRNPEACYNYCLRTGRPGGYCGGRSRITCFCFR
    

Molecular Weight4197.81 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)5.70

Net Charge (pH 7.4) 5.40

Charge Density (pH 7.0) 0.1583

GRAVY Index-0.71

Hydrophobic Moment 0.54

Boman Index-0.26

Instability Index66.29

Aliphatic Index 24.44

Aromaticity 0.1667

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1753.84

LogP -20.78

H-bond Donors 71.0

H-bond Acceptors 60.0

Rotatable Bonds 128.0

Heavy Atoms 291.0

Ring Count 9.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371450 VERIFIED: NO

Provenance & Taxonomy

OrganismTityus discrepans [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0423129 VERIFIED: YES