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MYP_056251
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Basic Information
AR K
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C127H195N29O25S2
Standard
Sequence
KWCVYAYVKVKGVLVKYKKCW
Physicochemical Analysis
2592.22 Da
9.76
5.73
5.49
0.2729
0.10
0.37
0.07
12.70
92.38
0.2381
15470.00
15595.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
893.71
-0.00
35.0
33.0
84.0
183.0
7.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0139185 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Arenicin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-20
Bio-Activity Profile
Antimicrobial
S. intermidius
4 μM
MIC
PaperRedesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina, by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization.
RECORD: Rec_0145268 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Arenicin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-20
Bio-Activity Profile
Antimicrobial
A. baumanii c.i
1 μM
MIC
PaperRedesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina, by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization.
RECORD: Rec_0156189 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MRSA ATCC 33591
2 μM
MIC
PMID31234579 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31234579/
RECORD: Rec_0182789 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
K562
7.7 μM
IC50
PaperPubMed PMID: 31234579 PMID31234579 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31234579/
RECORD: Rec_0201739 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 31234579 PMID31234579 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31234579/
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