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MYP_056216
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Basic Information
Cecropin(1-7)+Melittin(2-9) K3,6(Me 3 )
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
15 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KWXLFXKIGAVLKVL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0126513 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 3,6
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Leishmania mexicana pifanoi MHOM/VE/60/Ltrod
16.5
LC50
PMID20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20617807/
RECORD: Rec_0132927 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 3,6
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Acinetobacter baumannii ATCC 19606
2.0
IC50
PMID20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20617807/
RECORD: Rec_0152250 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 3,6
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Leishmania donovani MHOM/S.D./00/1S-2D promastigote
5.1
IC50
PMID20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20617807/
RECORD: Rec_0180452 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 3,6
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Leishmania mexicana pifanoi MHOM/VE/60/Ltrod
7.4
IC50
PMID20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20617807/
RECORD: Rec_0180476 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 3,6
Bio-Activity Profile
Hemolytic
sheep red blood cells
13.9 μM
Hemolysis
PMID20617807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20617807/
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