Peptide Database

Peptide NameLorvotuzumab mertansine

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length448 amino acids

Chemical FormulaC2191H3399N585O665S17

DescriptionStandard

        QVQLVESGGGVVQPGRSLRLSCAASGFTFSSFGMHWVRQAPGKGLEWVAYISSGSFTIYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARMRKGYAMDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight49120.05 Da

Isoelectric Point (pI)8.85

Net Charge (pH 7.0)9.55

Net Charge (pH 7.4) 8.55

Charge Density (pH 7.0) 0.0213

GRAVY Index-0.36

Hydrophobic Moment 0.51

Boman Index0.02

Instability Index44.84

Aliphatic Index 70.60

Aromaticity 0.0960

Extinction Coeff. Reduced 73800.00

Extinction Coeff. Oxidized 74425.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076696 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMonoclonal antibody

Tax ID32630

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer

RECORD: Rec_0248886 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

FamilyMonoclonal antibody

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer

RECORD: Rec_0266031 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

FamilyEnzyme

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Enzyme replacement

RECORD: Rec_0405543 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

FamilyImmunoglobulin

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Immunomodulatory