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MYP_056128
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Basic Information
Manduca Sexta Moricin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
42 amino acids
C208H355N63O50
Standard
Sequence
GKIPVKAIKQAGKVIGKGLRAINIAGTTHDVVSFFRPKKKKH
Physicochemical Analysis
4538.44 Da
11.36
9.93
9.61
0.2363
-0.30
0.78
-0.06
22.07
92.86
0.0476
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1838.35
-16.10
64.0
62.0
159.0
321.0
6.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0410530 VERIFIED: YES
Provenance & Taxonomy
Manduca sexta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 43 300
6.25 μg/mL
MIC
PMID18265434;12706633 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18265434/
RECORD: Rec_0426971 VERIFIED: YES
Provenance & Taxonomy
Manduca sexta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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