Peptide Database

Peptide NameBig gastrin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC170H251N45O50S

DescriptionStandard

        QLGPQVPAHLRTDLSKKQGPWAEEEAAYGWMDF
    

Molecular Weight3757.15 Da

Isoelectric Point (pI)4.90

Net Charge (pH 7.0)-2.15

Net Charge (pH 7.4) -2.41

Charge Density (pH 7.0) -0.0650

GRAVY Index-0.81

Hydrophobic Moment 0.44

Boman Index-0.01

Instability Index55.74

Aliphatic Index 56.36

Aromaticity 0.1212

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1518.81

LogP -12.21

H-bond Donors 50.0

H-bond Acceptors 50.0

Rotatable Bonds 118.0

Heavy Atoms 266.0

Ring Count 10.0

Amide Bonds 35.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0394389 VERIFIED: YES

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyBig gastrin

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Myotropic

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour