Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC746H1168N224O218S6

DescriptionStandard

        MSRVQFKQRESTDAIFVHCSATKPSQNVGVREIRQWHKEQGWLDVGYHFIIKRDGTVEAGRDEMAVGSHAKGHNHNSIGVCLVGGIDDKGKFDANFTPAQMQSLRSLLVTLLAKYEGAVLRAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight16955.01 Da

Isoelectric Point (pI)8.83

Net Charge (pH 7.0)3.19

Net Charge (pH 7.4) 2.48

Charge Density (pH 7.0) 0.0211

GRAVY Index-0.51

Hydrophobic Moment 0.75

Boman Index-0.07

Instability Index45.81

Aliphatic Index 74.24

Aromaticity 0.0795

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7143.60

LogP -73.96

H-bond Donors 252.0

H-bond Acceptors 235.0

Rotatable Bonds 569.0

Heavy Atoms 1194.0

Ring Count 28.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0295720 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella phage 3A_8767 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic