Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length165 amino acids

Chemical FormulaC832H1298N240O236S5

DescriptionStandard

        MPVINTHQNIAAFLDMLAYSEGTAMHPLTKNRGYDVIVTGIDGKPEIFTDYTDHPFAHGRPAKVFNRRGEKSTASGRYQQLYLYWPHYQKQLALPDFSPLSQDKLAIQLIRERGAIEDIKAGRIERAISRCRNIWASLPGAGYGQREHSLDKLVTVWRTAGGVMA
    

Molecular Weight18599.00 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)5.03

Net Charge (pH 7.4) 4.45

Charge Density (pH 7.0) 0.0305

GRAVY Index-0.43

Hydrophobic Moment 0.83

Boman Index-0.03

Instability Index39.26

Aliphatic Index 81.09

Aromaticity 0.0970

Extinction Coeff. Reduced 28420.00

Extinction Coeff. Oxidized 28420.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7651.64

LogP -72.28

H-bond Donors 268.0

H-bond Acceptors 252.0

Rotatable Bonds 608.0

Heavy Atoms 1313.0

Ring Count 34.0

Amide Bonds 177.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011546 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyLysozyme

Tax ID562

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic Glycosidase Hydrolase Non-hemolytic Non-ribosomal

RECORD: Rec_0104393 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli O141:H4 [Bacterium]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic Non-ribosomal

MethodQualitative functional evidence