Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC548H883N147O164S3

DescriptionStandard

        PDLTGYEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGKVHISKVFVTAIFSTPLDNPGPTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12250.95 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)4.13

Net Charge (pH 7.4) 3.93

Charge Density (pH 7.0) 0.0362

GRAVY Index0.01

Hydrophobic Moment 0.53

Boman Index0.12

Instability Index18.42

Aliphatic Index 96.58

Aromaticity 0.0702

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4964.39

LogP -54.06

H-bond Donors 176.0

H-bond Acceptors 173.0

Rotatable Bonds 404.0

Heavy Atoms 862.0

Ring Count 18.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050430 VERIFIED: NO

Provenance & Taxonomy

OrganismMachaerirhynchus nigripectus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria