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MYP_055930
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Basic Information
Naegleriapore A pore-forming peptide
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ Antiprotozoal
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
34 amino acids
C171H273N45O57S2
Standard
Sequence
DAECEICKFVIQQVEAFIESNHSQAEIQKELNKL
Physicochemical Analysis
3935.39 Da
4.54
-4.16
-4.46
-0.1223
-0.35
0.51
-0.03
66.13
94.71
0.0588
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1690.46
-15.80
56.0
56.0
139.0
275.0
3.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0026075 VERIFIED: YES
Provenance & Taxonomy
Naegleria fowleri [Protist]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus subtilis
PMID11948186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11948186/
RECORD: Rec_0104976 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0187693 VERIFIED: YES
Provenance & Taxonomy
Naegleria fowleri [Protist]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiprotozoal Cytotoxic
Escherichia coli K-12 D31
PaperPubMed PMID: 11948186 PMID11948186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11948186/
RECORD: Rec_0388278 VERIFIED: YES
Provenance & Taxonomy
Naegleria fowleri [Protist]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiprotozoal Cytotoxic
Bacillus subtilis strain 60015
PaperPubMed PMID: 11948186 PMID11948186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11948186/