Peptide Database

Peptide NameSLAY-screened peptide P5751

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC114H187N31O27S2

DescriptionStandard

        TALPRWYRMLRDMLLQTIPL
    

Molecular Weight2488.03 Da

Isoelectric Point (pI)10.74

Net Charge (pH 7.0)1.40

Net Charge (pH 7.4) 1.21

Charge Density (pH 7.0) 0.0699

GRAVY Index0.09

Hydrophobic Moment 0.81

Boman Index0.02

Instability Index60.03

Aliphatic Index 122.00

Aromaticity 0.1000

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 941.21

LogP -3.61

H-bond Donors 34.0

H-bond Acceptors 31.0

Rotatable Bonds 78.0

Heavy Atoms 174.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023513 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/