Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC756H1181N217O218S6

DescriptionStandard

        MASKVQFKPRTVTDAIFVHCSATKPSQDIGVDTIRMWHKQQGWLDVGYHFVIKRDGTVEEGRPVDVVGSHVKDWNYRSVGVCLVGGIDAKGKFEANFTPAQMNALRNKLAELKALYPQADIKAHHDVAPKACPSFDLQRWLNTNELVTSDRG
    

Molecular Weight16990.18 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)3.01

Net Charge (pH 7.4) 2.40

Charge Density (pH 7.0) 0.0198

GRAVY Index-0.39

Hydrophobic Moment 0.58

Boman Index-0.03

Instability Index35.17

Aliphatic Index 77.57

Aromaticity 0.0855

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6996.98

LogP -68.64

H-bond Donors 243.0

H-bond Acceptors 233.0

Rotatable Bonds 559.0

Heavy Atoms 1197.0

Ring Count 30.0

Amide Bonds 164.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0185164 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterobacter phage EV136_1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic