Peptide Database

Peptide NameSLAY-screened peptide P3031

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC93H161N21O29

DescriptionStandard

        SLLGSPSIIIAVIAAVPDSLT
    

Molecular Weight2037.40 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.75

Charge Density (pH 7.0) -0.0733

GRAVY Index1.53

Hydrophobic Moment 0.31

Boman Index0.56

Instability Index54.37

Aliphatic Index 171.90

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 766.19

LogP -6.74

H-bond Donors 26.0

H-bond Acceptors 28.0

Rotatable Bonds 62.0

Heavy Atoms 143.0

Ring Count 2.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0202267 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/