Peptide Database

Peptide NameBrevinin-2-AJ3 antimicrobial peptide (Frogs, amphibians, animals)

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC352H583N91O112S7

DescriptionStandard

        MFTMKKSLLVLFFLGTISLSLCEEERNADEDDGEMTEEEKRGLMSTFKQVGISAIKGAAQNVLGVLSCKLAKTC
    

Molecular Weight8106.39 Da

Isoelectric Point (pI)5.02

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0339

GRAVY Index0.06

Hydrophobic Moment 0.63

Boman Index0.06

Instability Index39.19

Aliphatic Index 90.95

Aromaticity 0.0541

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3298.75

LogP -32.42

H-bond Donors 117.0

H-bond Acceptors 117.0

Rotatable Bonds 287.0

Heavy Atoms 562.0

Ring Count 4.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0044996 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops jingdongensis [Animal]

FamilyBrevinin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0106429 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops [Animal]

FamilyBrevinin

Tax ID109940

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal