Peptide Database

Peptide NamePro-corazonin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC432H670N130O136S3

DescriptionStandard

        QTFTYSHGWTNGKRSTSLEELANRNAIQSDNVFANCELQKLRLLLQGNINNQLFQTPCELLNFPKRSFSENMINDHRQPAPTNNNY
    

Molecular Weight9956.93 Da

Isoelectric Point (pI)8.03

Net Charge (pH 7.0)0.93

Net Charge (pH 7.4) 0.58

Charge Density (pH 7.0) 0.0108

GRAVY Index-0.87

Hydrophobic Moment 0.56

Boman Index-0.15

Instability Index54.26

Aliphatic Index 66.98

Aromaticity 0.0930

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4411.58

LogP -54.43

H-bond Donors 148.0

H-bond Acceptors 142.0

Rotatable Bonds 331.0

Heavy Atoms 701.0

Ring Count 15.0

Amide Bonds 106.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0103515 VERIFIED: NO

Provenance & Taxonomy

OrganismApis mellifera [Animal]

FamilyCorazonin

Tax ID7460

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Other ModsAsn11 Amidation

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone

RECORD: Rec_0169191 VERIFIED: NO

Provenance & Taxonomy

OrganismApis mellifera [Animal]

FamilyPro-corazonin (Potential)

Tax ID7460

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods11:Asparagine amide

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Myotropic Receptor modulation

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0198168 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/