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MYP_055820
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Basic Information
Clavaspirin
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
23 amino acids
C119H186N34O25
Standard
Sequence
FLRFIGSVIHGIGHLVHHIGVAL
Physicochemical Analysis
2492.96 Da
9.78
1.11
0.70
0.0482
1.29
0.67
0.55
34.21
160.87
0.0870
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
900.37
-3.50
32.0
30.0
79.0
178.0
6.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0160511 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0171223 VERIFIED: NO
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Toxin
Has potent hemolytic activity
RECORD: Rec_0182385 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0194098 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Clavaspirin
7725
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperJ Pept Res. 2001 Dec;58(6):445-56. | http://www.ncbi.nlm.nih.gov/pubmed/12005415 PMID12005415 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12005415/
RECORD: Rec_0240331 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
20 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/12005415/ PMID12005415 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12005415/
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