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MYP_055801
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Basic Information
pVEC mutant
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C98H177N37O21
Standard
Sequence
LLIILRRRIRKQAHAHSK
Physicochemical Analysis
2209.69 Da
12.00
5.93
5.63
0.3296
-0.44
0.58
-0.35
98.19
141.11
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
978.34
-7.54
37.0
29.0
79.0
156.0
2.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0255508 VERIFIED: NO
Provenance & Taxonomy
Murinae gen. sp. [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperPatent US 2010/0279918 A1 Evidence URLhttps://patents.google.com/patent/US20100279918A1/en PatentUS 2010/0279918 A1
RECORD: Rec_0296457 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
pVEC
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
EGFP fusion
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID24746937 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24746937/
RECORD: Rec_0299054 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
2 μM
MIC50
PMID28556271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28556271/
RECORD: Rec_0361373 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Bio-Activity Profile
Antimicrobial Antimycobacterial Anticancer
Mycobacterium smegmatis
10 μM
MIC
PMID14656995 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14656995/
RECORD: Rec_0422891 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
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