‹ ›
MYP_055801
← PREVIOUS NEXT → BACK
Basic Information
pVEC mutant
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C98H177N37O21
Standard
Sequence
LLIILRRRIRKQAHAHSK
Physicochemical Analysis
2209.69 Da
12.00
5.93
5.63
0.3296
-0.44
0.58
-0.35
98.19
141.11
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
978.34
-7.54
37.0
29.0
79.0
156.0
2.0
18.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0183739 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
pVEC
10090
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Fluorescein/FITC labeling
Amidation
N-term detail: Labelled with fluorescein; lowercase source residues at positions 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18 denote stereochemical modification
Bio-Activity Profile
Cell-penetrating peptide
Human bowes melanoma cells
Fluorescence-based uptake assay
PMID16808894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16808894/
RECORD: Rec_0185473 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
pVEC
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID21996011 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21996011/
RECORD: Rec_0186819 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida glabrata
4 μM
MIC50
PMID28556271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28556271/
RECORD: Rec_0195447 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cell-penetrating peptide
Bovine erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/16137634/ PMID16137634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16137634/
RECORD: Rec_0221053 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
pVEC
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
N-term detail: Labelled with fluorescein
Bio-Activity Profile
Cell-penetrating peptide
AEC; HBCEC; End; Human bowes melanoma cells
Fluorescence-based uptake assay
PMID16808894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16808894/
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 3 of 4