Peptide Database

Peptide NamepVEC mutant

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium

Antimicrobial ▸ Antifungal

Antiparasitic ▸ Antimalarial

Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium

Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC98H177N37O21

DescriptionStandard

        LLIILRRRIRKQAHAHSK
    

Molecular Weight2209.69 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.93

Net Charge (pH 7.4) 5.63

Charge Density (pH 7.0) 0.3296

GRAVY Index-0.44

Hydrophobic Moment 0.58

Boman Index-0.35

Instability Index98.19

Aliphatic Index 141.11

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 978.34

LogP -7.54

H-bond Donors 37.0

H-bond Acceptors 29.0

Rotatable Bonds 79.0

Heavy Atoms 156.0

Ring Count 2.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0183739 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilypVEC

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralityall-D amino-acid peptide [D]

N-TermFluorescein/FITC labeling

C-TermAmidation

Other ModsN-term detail: Labelled with fluorescein; lowercase source residues at positions 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18 denote stereochemical modification

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHuman bowes melanoma cells

MethodFluorescence-based uptake assay

RECORD: Rec_0185473 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilypVEC

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

RECORD: Rec_0186819 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida glabrata

Activity4 μM

MethodMIC50

RECORD: Rec_0195447 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Hemolytic

TargetBovine erythrocytes

Activity50 μM

MethodHemolysis

RECORD: Rec_0221053 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilypVEC

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorescein/FITC labeling

C-TermAmidation

Other ModsN-term detail: Labelled with fluorescein

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetAEC; HBCEC; End; Human bowes melanoma cells

MethodFluorescence-based uptake assay

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