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MYP_055779
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Basic Information
Python Cathelicidin CATHPb1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
31 amino acids
C187H308N50O34
Standard
Sequence
KRFKKFFRKIKKGFRKIFKKTKIFIGGTIPI
Physicochemical Analysis
3800.76 Da
12.00
12.75
12.53
0.4113
-0.42
1.04
-0.18
-2.88
75.48
0.1935
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1413.89
-5.08
52.0
47.0
138.0
271.0
7.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0274655 VERIFIED: YES
Provenance & Taxonomy
Python bivittatus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory Immunomodulatory
E. faecium IS 1299
9.38 μg/mL
MIC
PaperPython Cathelicidin CATHPb1 Protects against Multidrug-Resistant Staphylococcal Infections by Antimicrobial-Immunomodulatory Duality.
RECORD: Rec_0286234 VERIFIED: YES
Provenance & Taxonomy
Python bivittatus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory Immunomodulatory
Aeromonas sobria
2.29 μM
MIC
PaperPython Cathelicidin CATHPb1 Protects against Multidrug-Resistant Staphylococcal Infections by Antimicrobial-Immunomodulatory Duality.
RECORD: Rec_0300840 VERIFIED: YES
Provenance & Taxonomy
Python bivittatu [Animal]
cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella oxytoca
75 μg/mL
MIC
PMID29466000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29466000/
RECORD: Rec_0316127 VERIFIED: YES
Provenance & Taxonomy
Python bivittatu [Animal]
cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans 08022821
18.75 μg/mL
MIC
PMID29466000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29466000/
RECORD: Rec_0319452 VERIFIED: YES
Provenance & Taxonomy
Python bivittatus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory Immunomodulatory
Pseudomonas aeruginosa ATCC 27853
9.38-37.5 μg/mL
MIC
PaperPython Cathelicidin CATHPb1 Protects against Multidrug-Resistant Staphylococcal Infections by Antimicrobial-Immunomodulatory Duality.
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