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MYP_055771
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Basic Information
DefDM
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
38 amino acids
C173H277N63O50S6
Standard
Sequence
GFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN
Physicochemical Analysis
4231.83 Da
9.43
5.87
5.48
0.1545
-0.61
0.72
-0.19
86.58
43.68
0.0789
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1860.94
-26.17
73.0
64.0
138.0
292.0
6.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0222731 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0300106 VERIFIED: YES
Provenance & Taxonomy
Dermacentor marginatus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa
PMID24747431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24747431/
RECORD: Rec_0300761 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]; Arthropoda [Animal]
9940; 6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID25588982 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25588982/
RECORD: Rec_0337865 VERIFIED: YES
Provenance & Taxonomy
Dermacentor marginatus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Micrococcus luteus CCM 144
0.2 μM
MIC
PMID24747431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24747431/
RECORD: Rec_0387916 VERIFIED: YES
Provenance & Taxonomy
Dermacentor silvarum [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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