Peptide Database

Peptide NameBrevinin-1-OA12

Function Ontology

Antimicrobial

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC125H202N28O28S3

DescriptionStandard

        FLPALIGMAANFLPTLFCKITKKC
    

Molecular Weight2641.31 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.1141

GRAVY Index1.03

Hydrophobic Moment 0.55

Boman Index0.37

Instability Index29.00

Aliphatic Index 110.00

Aromaticity 0.1250

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 876.65

LogP -3.11

H-bond Donors 31.0

H-bond Acceptors 34.0

Rotatable Bonds 84.0

Heavy Atoms 184.0

Ring Count 5.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004166 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax hubeiensis [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

RECORD: Rec_0330184 VERIFIED: NO