Peptide Database

Peptide NameS-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length443 amino acids

Chemical FormulaC2133H3340N590O672S11

DescriptionStandard

        MTQILGTGEGKTSSVAKEPVVERKPAQVFFESMALAASMSGYYAGPTATTLGNSLSLGAGTAAGVGEGVAGARVLAAPNPLTVALLAIFYSPSLNEGETEMLQNIRGDQLYQNLIHSQMMVGAFTRVNSTVIQGDYVPEYELREIARQNGTVHTRVRFRIEEDPESGELVSRSYEVGEKSGLDRVRVRFAKQLNKETWGFEDPSIKGTFVWSRSAGQGKFEWGSSQTTVHDGGAGGSTTPPTPIPEPRSVWGLPNPAPASLPPVPGTPIPEEQGPNIETLPIEDRDFNDFIIVDPMGGVPAIYVYFQKASVRDLEVDYYGNFEGRSRQGLYEVDHIPSKEAVRIYLKGTYPNLKDDIIEQMTDRVAAVAIPIEVHRQCSETYGGKNNSKFRTQDGGLVTQKVLDASNLEAAVDANWDVNAECLRNEYGVSDEKIEEIRAKRLC
    

Molecular Weight48353.60 Da

Isoelectric Point (pI)4.95

Net Charge (pH 7.0)-16.00

Net Charge (pH 7.4) -16.64

Charge Density (pH 7.0) -0.0361

GRAVY Index-0.39

Hydrophobic Moment 0.64

Boman Index0.00

Instability Index42.74

Aliphatic Index 77.90

Aromaticity 0.0790

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51465.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0331424 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyPyocin/Colicin

Tax ID573

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli